Raman Nanoparticle-Aided Imaging of Tumors Moves Closer to Human Trials

In 2008, a team of investigators at Stanford University’s Center for Cancer Nanotechnology Excellence demonstrated that it could use a technique known as nanoparticle-aided Raman spectroscopy to look at microscopic structures, including nascent tumors, deep inside the body. That team has now conducted extensive preclinical tests and shown that the gold nanoparticles can be safely administered into the colon and used with a Raman endoscope to image the inside of the large intestines. Reporting on their work in Small, Sanjiv Sam Gambhir and his colleagues describe their experiments applying radioactive labels to the gold nanoparticles in order to track their accumulation inside mice.

Raman Nanoparticle-Aided Imaging of Tumors Moves Closer to Human Trials

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